On March 29, 2023, naloxone (also known by the brand name Narcan) became available without a prescription at pharmacies across the United States. In an article on The Conversation, PERU’s Dr. Janice Pringle, along with University of Pittsburgh School of Pharmacy colleagues Dr. Lucas Berenbrok and Dr. Joni Carroll, explain why this decision is a significant step forward in reducing opioid overdoses and deaths.